Progetti di Ateneo
- Codice Progetto o altro Identificativo
- IG2021 N. 25795
- Denominazione Progetto
- AIRC Investigator Grant (IG)
- Tipologia di finanziamento
- Pubblica
- Tipologia ambito della fonte di finanziamento
- Ministeriale
- Fonte di finanziamento
- MIUR 2020 5x1000
- Call e/o Bando specifici
- Bando AIRC Investigator Grant 2021
- Referente Scientifico (nome e cognome)
- Cecilia Bucci
- Compagine Progettuale
- Università del Salento
- Data inizio
- 02/01/2022
- Data fine
- 01/04/2027
- Keywords
- Endocytosis; exosomes and/or endogenous microvescicles; drug response and/or resistance; cell signaling; cancer evolution
- Abstract
- The main goal of the project is to better understand the role of RAB7A in cancer cells studying processes governed by RAB7A and, in particular, their impact on cancer progression and chemoresistance. The specific aims of the project are the study of the role of RAB7A in EV biogenesis looking at the implications for cisplatin chemoresistance in ovarian cancer, and the study of the role of RAB7A in regulating mitochondria and EVs looking at the implications for cancer development and progression in pancreatic cancer.
- Ambito tecnologico produttivo
- Biotecnologie per la salute